MOLECULAR INTERACTION AND CELLULAR LOCATION OF RECA AND CHEW PROTEINS IN SALMONELLA ENTERICA DURING SOS RESPONSE AND THEIR IMPLICATION IN SWARMING

Molecular interaction and cellular location of RecA and CheW proteins in Salmonella enterica during SOS response and their implication in swarming

In addition to its role in DNA damage repair and recombination, the RecA protein, through its interaction with CheW, is involved in swarming motility, a form of flagella-dependent movement across surfaces.In order to better understand how SOS response modulates swarming, in this work the location of RecA and CheW proteins within the swarming cells

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Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7.

Retinol binding proteins (Rbps) are known as carriers for transport and targeting of retinoids to their metabolizing enzymes.Rbps are also reported to function in regulating the homeostatic balance of retinoid metabolism, as their level of retinoid occupancy impacts the activities of retinoid metabolizing enzymes.Here we used zebrafish as a model t

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A multi-cancer early detection blood test using machine learning detects early-stage cancers lacking USPSTF-recommended screening

Abstract US Preventive Services Task Force (USPSTF) guidelines recommend single-cancer screening for select cancers (e.g., breast, cervical, colorectal, iphone 14 price miami lung).Advances in genome sequencing and machine learning have facilitated the development of blood-based multi-cancer early detection (MCED) tests intended to complement singl

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Application of Plackett-Burman Factorial Design in The Development of Curcumin Loaded Eudragit E 100 Nanoparticles

The present study was aimed to fabricate Curcumin loaded Eudragit E 100 polymeric nanoparticles and to study the effect of various manufacturing parameters on the average particle size, span, uniformity and surface area of the prepared polymeric nanoparticles by utilizing Plackett-Burman experimental designs.Curcumin loaded Eudragit E 100 nanoparti

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